2017
Guan H, Yang H, Yang M, Yanagisawa D, Bellier JP, Mori M, Takahata S, Nonaka T, Zhao S, Tooyama I: Mitochondrial ferritin protects SH-SY5Y cells against H2O2-induced oxidative stress and modulates a-synuclein expression. Exp Neurol 291: 51-61, 2017.

Beller JP, Xie Y, Farouk SM, Sakaue Y, Toooyama I, Kimura H: Immunohistochemical and biochemical evidence for the presence of serotonin-containing neurons and nerve fibers in the octopus arm. Brain Sttruct Funct. DOI 10.1007/s00429-017-1385-3.

Higaki S, Shimada M, Kawamoto K, Todo T, Kawasaki T, Tooyama I, Fujioka Y, Sakai N, Takada T: In vitro differentiation of fertile sperm from cryopreserved spermatogonia of the endangered endemic cyprinid honmoroko (Gnathopogon caerulescens). Sci Rep. 7:42852, DOI: 10.1038/srep42852.

Yang M, Yang H, Guan H, Kato T, Mukaisho K, Sugihara H, Ogasawara K, Terada T, Tooyama I: Characterization of a Novel Monoclonal Antibody against Human Mitochondrial Ferritin and its Immunohistochemical Application in Human and Monkey Substantia Nigra. Acta Histochem Cytochem. 50: 49-55, 2017.

Shiino A, Chen Y-W, Tanigaki K, Yamada A, Vigers P, Watanabe T, Tooyama I, Akiguchi I: Sex-related difference in human white matter volumes studied: Inspection of the corpus callosum and other white matter by VBM. Sci Rep. 3;7:39818, 2017.

Ito T, Tanaka-Mizunio S, Iwashita N, Tooyama I, Shiino A, Miura K, Fukui S: Proton magnetic resonance spectroscopy (1H-MRS) assessment of metabolite status of the anterior cingulate cortex in chronic pain patients and healthy controls. J Pain Research10:287-293, 2017.

Ibrahim NF, Yanagisawa D, Durania LW, Hamezaha HS, HDamanhuri HD, Wan Ngahb WZ, Tsuji M, Kiuchi Y, Ono K, Tooyama I: Tocotrienol-rich fraction modulates amyloid pathology and improves cognitive function in AβPP/PS1 mice. J Alzheimer Dis 55:597-612, 2017.

Kitamura Y, Inden M, Kimoto Y, Takata K, Yanagisawa D, Hijioka M, Ashihara E, Tooyama I, Shimohama S, Ariga H: Effects of a DJ-1-Binding Compound on Spatial Learning and Memory Impairment in a Mouse Model of Alzheimer's Disease. J Alzheimer Dis 55:67-72, 2017.

Yanagisawa D, Oda K, Inden M, Morikawa S, Inubushi T, Taniguchi T, Hijioka M, Kitamura Y, Tooyama I: Fluorodopa is a promising fluorine-19 MRI probe for evaluating striatal dopaminergic function in a rat model of Parkinson’s disease. J Neurosci Res (in press).


2016
Zhao L, Yang H, Amano T, Xu M, Qin H, Zheng L, Takahashi A, Zhao S, Tooyama I, Murakami T, Komatsu N: Efficient Delivery of Chlorin e6 into Ovarian Cancer Cell with Octalysine Conjugated Superparamagnetic Iron Oxide Nanoparticle for Effective Photodynamic Therapy. J Mater Chem B 4: 7741—7748, 2016.

Abdelalim EM, Bellier JP, Tooyama I: Localization of Brain Natriuretic Peptide Immunoreactivity in Rat Spinal Cord. Frontiers in Neuroanatomy 10: e116, 2016.

Wang X, Yang H, Yanagisawa D, Bellier JP, Morino K, Zhao S, Liu P, Vigers P, Tooyama I.: Mitochondrial ferritin affects mitochondria by stabilizing HIF-1α in retinal pigment epithelium: implications for the pathophysiology of age-related macular degeneration. Neurobiol Aging. 2016 Aug 12;47:168-179. doi: 10.1016/j.neurobiolaging.2016.07.025. [Epub ahead of print] PMID: 27599360

Ogawa T, Irikawa N, Yanagisawa D, Shiino A, Tooyama I, Shimizu T.: Taste detection and recognition thresholds in Japanese patients with Alzheimer-type dementia. Auris Nasus Larynx. 2016 Jul 11. pii: S0385-8146(16)30197-3. doi: 10.1016/j.anl.2016.06.010. [Epub ahead of print] PMID: 27427537

Yang M, Yang H, Guan H, Bellier JP, Zhao S, Tooyama I.: Mapping of mitochondrial ferritin in the brainstem of Macaca fascicularis. Neuroscience. 2016 Jul 22;328:92-106. doi: 10.1016/j.neuroscience.2016.04.035. Epub 2016 Apr 28. PMID: 27133573

Seita Y, Tsukiyama T, Iwatani C, Tsuchiya H, Matsushita J, Azami T, Okahara J, Nakamura S, Hayashi Y, Hitoshi S, Itoh Y, Imamura T, Nishimura M, Tooyama I, Miyoshi H, Saitou M, Ogasawara K, Sasaki E, Ema M.: Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body. Sci Rep. 2016 Apr 25;6:24868. doi: 10.1038/srep24868. PMID: 27109065

Inden M, Takata K, Yanagisawa D, Ashihara E, Tooyama I, Shimohama S, Kitamura Y.: α4 nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior. Neurochem Int. 2016 Mar;94:74-81. doi: 10.1016/j.neuint.2016.02.008. Epub 2016 Feb 18. PMID: 26911419

Tooyama I, Yanagisawa D, Taguchi H, Kato T, Hirao K, Shirai N, Sogabe T, Ibrahim NF, Inubushi T, Morikawa S: Amyloid imaging using fluorine-19 magnetic resonance imaging (19F-MRI). Ageing Res Rev, s1568-1637;(15)300444-1, 2016.

Sonoda Y, Tooyama I, Mukai H, Maeda K, Akiyama H, Kawamata T: 1S6 kinase phosphorylated at T229 is involved in tau and actin pathologies in Alzheimer's disease. Neuropathology36:325-332, 2016.


2015
Yanagisawa D, Taguchi H, Morikawa S, Kato T, Hirao K, Shirai N, Tooyama I: Novel curcumin derivatives as potent inhibitors of amyloid b aggregation. Biochem Biophys Rep 4: 357-368, 2015.

Wada Y, Iwasaki Y, Abe T, Wada K, Tooyama I, Ikemura T: CG-containing oligonucleotides and transcription factor-binding motifs are enriched in human pericentric regions. Genes Genet Syst 90: 43-53, 2015.

Vipers P, Shiino A, Tooyama I: Diagnosis of amyloid-positive mild cognitive impairment using structural magnetic resonance imaging: The worth of multiple regions of interest. Integr Mol Med 2: 205-213, 2015.

Kato T, Konishi Y, Shimohama S, Beach TG, Akatsu H, Tooyama I: Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients. Neurosci Lett 591: 19-24, 2015.

Yang H, Guan H, Yang M, Liu Z, Takeuchi S, Yanagisawa D, Vincent SR, Zhao S, Tooyama I: Upregulation of Mitochondrial Ferritin by Proinflammatory Cytokines: Implications for a Role in Alzheimer's Disease. J Alzheimers Dis 45: 797-811, 2015.

McClure R, Yanagisawa D, Stec D, Abdollahian D, Koktysh D, Xhillari D, Jaeger R, Stanwood G, Chekmenev E, Tooyama I, Gore JC: Pham W. Inhalable curcumin: offering the potential for translation to imaging and treatment of Alzheimer's disease. J Alzheimers Dis 44: 283-295, 2015.

Yanagisawa D, Ibrahim NF, Taguchi H, Morikawa S, Hirao K, Shirai N, Sogabe T, Tooyama I: Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice. Neurobiol Aging 36: 201-210, 2015.

Taguchi H, Yanagisawa D, Morikawa S, Hirao K, Shirai N, Tooyama I: Synthesis and tautomerism of curcumin derivatives and related compounds. Aust J Chem 68: 224-229, 2015.


2014
Nanjo T, Fukuhara T, Kameshima N, Yanagisawa D, Shimizu S, Shimizu T, Shiino A, Akatsu H, Yamamoto T, Tooyama I: Development of a method to measure Aβ42 in nasal cavity samples and its application in normal human volunteers. J Brain Sci 44: 5-23, 2014.

Tamiya G, Makino S, Hayashi M, Abe A, Numakura C, Ueki M, Tanaka A, Ito C, Toshimori K, Ogawa N, Terashima T, Maegawa H, Yanagisawa D, Tooyama I, Tada M, Onodera O, Hayasaka K: A mutation of COX6A1 causes a recessive axonal or mixed form of Charcot-Marie-Tooth disease. Am J Hum Genet 95: 294-300, 2014.

Magdeldin S, Yamamoto T, Tooyama I, Abdelalim EM: New proteomic insights on the role of NPR-A in regulating self-renewal of embryonic stem cells. Stem Cell Rev 10: 561-572, 2014.

Miwa M, You G, Tanaka H, Taniguchi S, Fujii T, Kamemura K, Suzaki M, Isono T, Tooyama I, Tanaka M, Srivatanakul P, Viwatthanasittiphong C, Sangrajrang S, Khuhaprema T: Analysis of new biomarkers for cholangiocarcinoma. J Hepatobiliary Pancreat Sci 21: 397-398, 2014.

Masuda C, Takeuchi S, Bisem JN, Vincent SR, Tooyama I: Immunohistochemical Localization of an Isoform of TRK-Fused Gene-Like Protein in the Rat Retina. Acta Histochem Cytochem 47: 75-83, 2014.

Abdelalim EM, Tooyama I: Knockdown of p53 suppresses Nanog expression in embryonic stem cells. Biochem Biophys Res Commun 443: 652-657, 2014.

Yanagisawa D, Taguchi H, Ibrahim NF, Morikawa S, Shiino A, Inubushi T, HIrao K, Shirai N, Sogabe T, Tooyama I: Preferred features of a fluorine-19 MRI probe for amyloid detection in the brain. J Alzheimer’s Dis 39: 617-631 2014..

Sakaue Y, Bellier JP, Kimura S, D'Este L, Takeuchi Y, Kimura H. Immunohistochemical localization of two types of choline acetyltransferase in neurons and sensory cells of the octopus arm. Brain Struct Funct. Brain Struct Funct 219: 323-341, 2014. PMID:23354679


2013
Higaki S, Koyama Y, Shimada M, Ono Y, Tooyama I, Fujioka Y, Sakai N, Ikeuchi T, Takada T: Response to fish specific reproductive hormones and endocrine disrupting chemicals of a Sertoli cell line expressing endogenous receptors from an endemic cyprinid Gnathopogon caerulescens. Gen Comp Endocr 191: 65-73, 2013.

Abdelalim EM, Bellier JP, Tooyama I. Expression of NPR-B in neurons of the dorsal root ganglia of the rat. Peptides 43: 56-61, 2013.

Yang H, Yang M, Guan H, Liu Z, Zhao S, Takeuchi S, Yanagisawa D, Tooyama I. Mitochondrial ferritin in neurodegenerative diseases. Folia Histochem Cytobiol. in press. PMID:23916831

Takeuchi S, Matsuda W, Tooyama I, Yasuhara O. Kainic acid induces expression of caveolin-1 in activated microglia in rat brain. Folia Histochem Cytobiol. 51(1):25-30, 2013. PMID:23690214

Yezdimer EM, Umemoto T, Yamada H, Makino S, Tooyama I. Visualizing Hepatic Copper Release in Long-Evans Cinnamon Rats Using Single-Photon Emission Computed Tomography. Appl Biochem Biotechnol 170: 1138-1150, 2013. PMID:23645415

Kameshima N, Yanagisawa D, Tooyama I. β-Amyloid peptide (1-40) in the brain reaches the nasal cavity via a non-blood pathway. Neurosci Res 76: 169-172, 2013. PMID:23603507

Abdelalim EM, Bellier JP, Tooyama I. Expression of NPR-B in neurons of the dorsal root ganglia of the rat. Peptides. 43:56-61, 2013. PMID:23454171

Makino S, Masuda C, Ando S, Tamiya G, Tooyama I: Generation of a monoclonal antibody specifically recognizing with neuron-specific TATA-box binding protein-associated factor 1 (TAF-1). Antibodies 2: 1-8, 2013.

Koga T, Bellier JP, Kimura H, Tooyama I: Immunoreactivity for choline acetyltransferase of peripheral-type (pChAT) in the trigeminal ganglion neurons of the non-human primate Macaca fascicularis. Acta Histochem Cytoc 46: 59-64, 2013.

Hanada K, Kishimoto S, Bellier JP, Kimura H. Peripheral choline acetyltransferase in rat skin demonstrated by immunohistochemistry. Cell Tissue Res. 351(3):497-510, 2013. PMID:23250574


2012
Bisem NJ, Takeuchi S, Imamura T, Abdelalim EM, Tooyama I. Mapping of FGF1 in the Medulla Oblongata of Macaca fascicularis. Acta Histochem Cytochem. 26;45(6):325-34, 2012. PMID:23378676

Kato T, Tamiya G, Koyama S, Nakamura T, Makino S, Arawaka S, Kawanami T, Tooyama I. UBR5 Gene Mutation Is Associated with Familial Adult Myoclonic Epilepsy in a Japanese Family. ISRN Neurol. 2012:508308, 2012. PMID:23029623

Casini A, Vaccaro R, D'Este L, Sakaue Y, Bellier JP, Kimura H, Renda TG. Immunolocalization of choline acetyltransferase of common type in the central brain mass of Octopus vulgaris. Eur J Histochem. 56(3):e34, 2012. PMID:23027350

Nishimura M, Nakamura S, Kimura N, Liu L, Suzuki T, Tooyama I. Age-related modulation of γ-secretase activity in non-human primate brains. J Neurochem, 123(1):21-8, 2012. PMID:22817324

Makino S, Umemoto T, Yamada H, Yezdimer EM, Tooyama I. In vivo detection of copper ions by magnetic resonance imaging using a prion-based contrast agent. Appl Biochem Biotechnol. 168(3):504-18, 2012. PMID:22810201

Inden M, Abe M, Minamino H, Takata K, Yoshimoto K, Tooyama I, Kitamura Y. Effect of selective serotonin reuptake inhibitors via 5-HT1A receptors on L-DOPA-induced rotational behavior in a hemiparkinsonian rat model. J Pharmacol Sci. 119(1):10-9, 2012. PMID:22510520

Takeuchi S, Masuda C, Maebayashi H, Tooyama I. Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem. Acta Histochem Cytochem.45(1):57-64, 2012. PMID:22489105

Maebayashi H, Takeuchi S, Masuda C, Makino S, Fukui K, Kimura H, Tooyama I. Expression and Localization of TRK-Fused Gene Products in the Rat Brain and Retina. Acta Histochem Cytochem. 29;45(1):15-23, 2012. PMID: 22489101

Abdelalim EM, Tooyama I. The p53 inhibitor, pifithrin-α, suppresses self-renewal of embryonic stem cells. Biochem Biophys Res Commun. 420(3):605-10, 2012. PMID:22445757

Kameshima N, Nanjou T, Fukuhara T, Yanagisawa D, Tooyama I. Correlation of Aβ deposition in the nasal cavity with the formation of senile plaques in the brain of a transgenic mouse model of Alzheimer's disease. Neurosci Lett.;513(2):166-9, 2012. PMID:22343315

Park D, Lee HJ, Joo SS, Bae DK, Yang G, Yang YH, Lim I, Matsuo A, Tooyama I, Kim YB, Kim SU. Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction. Exp Neurol.;234(2):521-6, 2012. PMID:22245157

Akatsu H, Hori A, Yamamoto T, Yoshida M, Mimuro M, Hashizume Y, Tooyama I, Yezdimer EM. Transition metal abnormalities in progressive dementias. Biometals. 25(2):337-50, 2012. PMID:22080191

Park D, Joo SS, Kim TK, Lee SH, Kang H, Lee HJ, Lim I, Matsuo A, Tooyama I, Kim YB, Kim SU. Human neural stem cells overexpressing choline acetyltransferase restore cognitive function of kainic acid-induced learning and memory deficit animals. Cell Transplant. 21(1):365-71, 2012. PMID:21929870

Abdelalim EM, Tooyama I. NPR-C protects embryonic stem cells from apoptosis by regulating p53 levels. Stem Cells Dev. 21(8):1264-71, 2012. PMID:21846177

Shiino A, Akiguchi I, Watanabe T, Shirakashi Y, Nozaki K, Tooyama I, Inubushi T. Morphometric characterization of Binswanger's disease: comparison with Alzheimer's disease. Eur J Radiol. 81(9):2375-9, 2012. PMID:21708443

2011
Wang L, Yang H, Zhao S, Sato H, Konishi Y, Beach TG, Abdelalim EM, Bisem NJ, Tooyama I. Expression and localization of mitochondrial ferritin mRNA in Alzheimer's disease cerebral cortex. PLoS One.6(7):e22325, 2011. PMID:21799823

Sako W, Morigaki R, Kaji R, Tooyama I, Okita S, Kitazato K, Nagahiro S, Graybiel AM, Goto S. Identification and localization of a neuron-specific isoform of TAF1 in rat brain: implications for neuropathology of DYT3 dystonia. Neuroscience. 189:100-7, 2011. PMID:21616129

Yanagisawa D, Amatsubo T, Morikawa S, Taguchi H, Urushitani M, Shirai N, Hirao K, Shiino A, Inubushi T, Tooyama I. In vivo detection of amyloid β deposition using ¹⁹F magnetic resonance imaging with a ¹⁹F-containing curcumin derivative in a mouse model of Alzheimer's disease. Neuroscience. 184:120-7, 2011. PMID:21497641

Abdelalim EM, Tooyama I. Mapping of NPR-B immunoreactivity in the brainstem of Macaca fascicularis. Brain Struct Funct. 216(4):387-402, 2011. PMID:21455797

Abdelalim EM, Tooyama I. NPR-A regulates self-renewal and pluripotency of embryonic stem cells. Cell Death Dis. 2:e127, 2011. PMID:21390061

Bellier JP, Kimura H. Peripheral type of choline acetyltransferase: biological and evolutionary implications for novel mechanisms in cholinergic system. J Chem Neuroanat. 42(4):225-35, 2012. PMID:21382474

Morimoto K, Horio J, Satoh H, Sue L, Beach T, Arita S, Tooyama I, Konishi Y. Expression profiles of cytokines in the brains of Alzheimer's disease (AD) patients compared to the brains of non-demented patients with and without increasing AD pathology. J Alzheimers Dis. 25(1):59-76, 2011. PMID:21368376

Yanagisawa D, Taguchi H, Yamamoto A, Shirai N, Hirao K, Tooyama I. Curcuminoid binds to amyloid-β1-42 oligomer and fibril. J Alzheimers Dis. 24 Suppl 2:33-42, 2011. PMID:21335654

D'Este L, Casini A, Kimura S, Bellier JP, Ito E, Kimura H, Renda TG. Immunohistochemical demonstration of cholinergic structures in central ganglia of the slug (Limax maximus, Limax valentianus). Neurochem Int.;58(5):605-11, 2011. PMID:21315127

Matsuo A, Bellier JP, Nishimura M, Yasuhara O, Saito N, Kimura H. Nuclear choline acetyltransferase activates transcription of a high-affinity choline transporter. J Biol Chem. 286(7):5836-45, 2011. PMID:21163949

Casini A, Vivacqua G, Pontieri FE, Kimura H, Bellier JP, D'Este L, Renda TG. Choline acetyltransferase of the common type immunoreactivity in the rat brain following different heroin treatments: a pilot study. J Chem Neuroanat. 41(2):111-21, 2011. PMID:21184823

2010
Nakahara H, Konishi Y, Beach TG, Yamada N, Makino S, Tooyama I. Infiltration of T lymphocytes and expression of icam-1 in the hippocampus of patients with hippocampal sclerosis. Acta Histochem Cytochem. 43(6):157-62, 2010. PMID:21245982

Amatsubo T, Yanagisawa D, Morikawa S, Taguchi H, Tooyama I. Amyloid imaging using high-field magnetic resonance. Magn Reson Med Sci. 9(3):95-9, 2010. PMID:20885081

Takeuchi S, Fujiwara N, Ido A, Oono M, Takeuchi Y, Tateno M, Suzuki K, Takahashi R, Tooyama I, Taniguchi N, Julien JP, Urushitani M. Induction of protective immunity by vaccination with wild-type apo superoxide dismutase 1 in mutant SOD1 transgenic mice. J Neuropathol Exp Neurol. 69(10):1044-56, 2010. PMID:20838241

Wang L, Sato H, Zhao S, Tooyama I. Deposition of lactoferrin in fibrillar-type senile plaques in the brains of transgenic mouse models of Alzheimer's disease. Neurosci Lett. 481(3):164-7, 2010. PMID:20599473

Yanagisawa D, Shirai N, Amatsubo T, Taguchi H, Hirao K, Urushitani M, Morikawa S, Inubushi T, Kato M, Kato F, Morino K, Kimura H, Nakano I, Yoshida C, Okada T, Sano M, Wada Y, Wada KN, Yamamoto A, Tooyama I. Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease. Biomaterials. 31(14):4179-85, 2010. PMID:20181392

Abdelalim EM, Tooyama I. NPR-C is expressed in the cholinergic and dopaminergic amacrine cells in the rat retina. Peptides. 31(1):180-3, 2010. PMID:19878700

Urushitani M, Sato T, Bamba H, Hisa Y, Tooyama I. Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43. J Neurosci Res. 88(4):784-97, 2010. PMID:19798749

2009
Yanagida T, Tsushima J, Kitamura Y, Yanagisawa D, Takata K, Shibaike T, Yamamoto A, Taniguchi T, Yasui H, Taira T, Morikawa S, Inubushi T, Tooyama I, Ariga H. Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. Oxid Med Cell Longev.2(1):36-42, 2009. PMID:20046643

Sato T, Takeuchi S, Saito A, Ding W, Bamba H, Matsuura H, Hisa Y, Tooyama I, Urushitani M. Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons. Neuroscience. 164(4):1565-78, 2009. PMID:19782731

Oda K, Makino S, Masuda C, Yoshiki T, Kitamura Y, Takata K, Yanagisawa D, Taniguchi T, Tooyama I. The mRNA distribution of C7orf24, a gamma-glutamyl cyclotransferase, in rat tissues. J Histochem Cytochem. 57(12):1121-6, 2009. PMID:19687470

Abdelalim EM, Tooyama I. BNP signaling is crucial for embryonic stem cell proliferation. PLoS One. 4(4):e5341, 2009. PMID:19399180

An L, Sato H, Konishi Y, Walker DG, Beach TG, Rogers J, Tooyama I. Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease. Neurosci Lett. 452(3):277-80, 2009. PMID:19348738

Saito A, Sato T, Okano H, Toyoda K, Bamba H, Kimura S, Bellier JP, Matsuo A, Kimura H, Hisa Y, Tooyama I. Axotomy alters alternative splicing of choline acetyltransferase in the rat dorsal motor nucleus of the vagus nerve. J Comp Neurol. 513(2):237-48, 2009. PMID: 19137611

Amatsubo T, Morikawa S, Inubushi T, Urushitani M, Taguchi H, Shirai N, Hirao K, Kato M, Morino K, Kimura H, Nakano I, Yoshida C, Okada T, Sano M, Tooyama I. Trifluoromethoxy-benzylated ligands improve amyloid detection in the brain using (19)F magnetic resonance imaging. Neurosci Res. 63(1):76-81, 2009. PMID:18996420

2008
Abdelalim EM, Masuda C, Bellier JP, Saito A, Yamamoto S, Mori N, Tooyama I. Distribution of natriuretic peptide receptor-C immunoreactivity in the rat brainstem and its relationship to cholinergic and catecholaminergic neurons. Neuroscience. 155(1):192-202, 2008. PMID:18571869

D'Este L, Kimura S, Casini A, Matsuo A, Bellier JP, Kimura H, Renda TG. First visualization of cholinergic cells and fibers by immunohistochemistry for choline acetyltransferase of the common type in the optic lobe and peduncle complex of Octopus vulgaris. J Comp Neurol. 509(6):566-79, 2008. PMID: 18543295

Urushitani M, Ezzi SA, Matsuo A, Tooyama I, Julien JP. The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS. FASEB J. 22(7):2476-87, 2008. PMID:18337461

Abdelalim EM, Masuda C, Tooyama I. Expression of natriuretic peptide-activated guanylate cyclases by cholinergic and dopaminergic amacrine cells of the rat retina. Peptides.29(4):622-8, 2008. PMID:18192083

Wilberding A, Morimoto K, Satoh H, Harano K, Harano T, Arita S, Tooyama I, Konishi Y. Multiple cytokines are involved in the early events leading to the Alzheimer's disease pathology. Tottori Rinsho Kagaku Kenkyukai Shi. 1(2):359-373, 2008. PMID: 22586434

Yanagisawa D, Kitamura Y, Inden M, Takata K, Taniguchi T, Morikawa S, Morita M, Inubushi T, Tooyama I, Taira T, Iguchi-Ariga SM, Akaike A, Ariga H. DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats. J Cereb Blood Flow Metab. 28(3):563-78, 2008. PMID:17882163