NEWS

Dec. 26, 2014 We had a final session of the year.
Nov. 29-Dec. 1, 2014 Japan Society for Dementia Research 33rd Annual meeting was held in Yokohama Pacifico. 4 titles were announced from MNRC.
Nov.　 25, 2014　We held the 18th Molecular Neuroscience Research Center International Symposium.

Oct.　 21, 2014　 Ms. Hamizah Shahirah Binti Hamezah from Universiti Kebangsaan Malaysia and Mr. Liu Yuyan from China Medical University visited the presider room and talked with president Shiota and vice-president Horiike
.
Oct. 　1, 2014　Welcome new students; Mr. Liu Ziyi entered PhD course at Shiga University of Medical Science. Ms. Hamizah Shahirah Binti Hamezah, supported by Japanese government （MONBUKAGAKUSHO: MEXT) scholarship, arrived at SUMS.

Oct. 　1, 2014　Dr. Chiaki Masuda and Dr. Liu Lei have obtained PhD thesis from Shiga University of Medical Science.

Sep. 30, 2014　We had a farewell party for Dr. Sameh Farouk from Suze Canal University in Egypt.

Sep. 27, 2014　Dr. Shigeko Takeuchi and Mingchun Yang presented their data at the 55th Meeting for Japan Society of HIstochemistry and Cytochemistry.
　P01 Shigeko Takeuchi and Ikuo Tooyama: Expression of Trk-fused gene proteins in monoaminergic neurons in the rat brainstem.
　P02 Mingchun Yang, Hongkuan Yang, Guan Hongpeng, Liu Zyri and Ikuo Tooyama: Immunohistochmcial localization of mitochondrial ferritin in the brainstem of Macaca fascicularis.

Jun. 27, 2014　We celebrated a farewell party for Dr. Steven Vincent.

Apr. 7, 2014 　 "OHANAMI" sakura tour in the Hikone Castle.

Apr. 2, 2014　　Dr. Sameh Farouk joined us.

Apr. 2, 2014 　　We held a ceremony of the appointment letter.

Mar. 25, 2014　 We held an invited lecture of Prof. Mohd Hanafi Ahmad Damanhuri of UKM.

Mar. 12, 2014　 We cerebrated a farewell party.

Mar. 10, 2014　 Ms. NAOMI J. Bisem and Dr. Takeshi Kitanishi have obtained Ph.D. from the Shiga university of Medical Science.

Feb. 18, 2014　 We visited　UKM Medical Molecular Biology Institute) and had a meeting concerning the international joint research project concerning the cognitive impairment of elderly people supported by Ministry of Higher Education Malaysia.

Feb. 17, 2014 　Held the ceremonial signing of the research project agreement between UNIVERSITI KEBANGSAAN MALAYSIA (Department of Biochemistry and UKM Medical Molecular Biology Institute) and Shiga University of Medical Science (Molecular Neuroscience Center).

Jan. 28, 2014 　PhD thesis of Bisem J Naomi-san has ended.

Jan. 6, 2014 　Prof. Steven Vincent has arrived.

Jan. 1, 2013 　Prof. Tooyama posted a message for the New Year.

Dec. 20, 2013 　The year-end party was held.

Oct. 15, 2013　 We had a farewell party for Dr. Urushitani and Ms. Shodai.

Oct. 4, 2013     The 25th anniversary MNRC International Symposium was held at Royal Oak Hotel (Otsu).

Oct. 2, 2013     A paper concerning 19F MRI probe Shiga-X22 was accepted in Journal of Alzheimers Disease.

Oct. 1, 2013     Guan Hongpeng entered Graduate School of Medicine, SUMS.

Oct. 1, 2013     Lui Lei have been employed as a Assistant Professor.

Sep. 27, 2012   Guan Hongpeng got a young investigator award at the 40th Annual Meeting of the Japan Society of Brain Science.

Aug 30, 2013    A paper entitled “Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1” has been published in Journal of Neurochemistry.

Jul 31, 2013     A review paper entitled “Mitochondrial ferritin in neurodegenerative diseases” has been published in Neuroscience Research.

Jun 6, 2013     A paper entitled “Kainic acid induces expression of caveolin-1 in activated microglia in rat brain” has been published in Folia Histochemica et Cytobiologica.

May 4, 2013     A paper entitled “Beta-amyloid peptide (1-40) in the brain reaches the nasal cavity via a non-blood pahway” has been published in an online version of Neuroscience Research.

Apr. 5, 2013     A paper entitled “Aberrant assembly of RNA-recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein-43 (TDP-43)”has been published in an online version of Journal of Biological Chemistry.

Apr. 1, 2013     Two researchers have been employed as new staffs at MNRC.

Feb. 27, 2013     A paper concerning “NPR-B in rat dorsal root ganglia” has been published in an online version of Peptides.

Feb. 1, 2013     A paper concerning cholinergic neurons in the octopus has been published in on line version of Brain Structure and Function.

Jan. 9, 2013 　MNRC members attended “The Evening for International Exchange”, a social party, held at SMUS.

Jan. 8, 2013     A paper concerning “pChAT in glabrous skin” has been published in an online version of Cell Tissue Res.

Dec. 27, 2012 　MNRC members party was held at Umenohana restaurant in Estopia Hotel as the year-end party of 2012.

Nov. 16, 2012 　The 16th MNRC international symposium entitled “Initial Meeting for international collaborative study between Universiti Kebangsaan Malaysia and Shiga University of Medical Science on cognitive functions in aged people” was held.

Nov. 13, 2012 　The 15th MNRC international symposium entitled “New avenue for developing disease-modifying therapies of Alzheimer's disease: Reassessment of Amyloid-β as the primary target” was held at SUMS
.
Nov. 8, 2012     Assistant Professor Daijiro Yanagisawa won a Young Investigator award at The 24th Annual Meeting of the Japanese Society to Cerebral Blood Flow at Hiroshima.

Nov. 7, 2012     Professor Magoha and Professor Omwandho, Vice Chancellor and Dean of Medicine from Nairobi University, respectively and also Dr. Mpoke, Director of Kenya Medical Research Institute, visited SUMS for signing ceremony of sister school relationship. Professor Ikuo Tooyama, Director of MNRC, and Ms.Bisem, a Graduate Student from Kenya, attended the commemorative event.

Oct. 16, 2012    The international joint research project concerning the cognitive impairment of elderly people supported by Ministry of Higher Education Malaysia was started in seven universities in Malaysia and MNRC, SUMS. Ikuo Tooyama (director of MNRC) attended the first joint meeting held at UKM.

Oct. 15, 2012    Ikuo Tooyama (director of MNRC) gave a commemorative lecture in the signing ceremony of sister school relationship between Universiti Kebangsaan Malaysia (UKM) and SUMS held at UKM.

Oct. 12, 2012     A paper concerning “immunolocalization of choline acetyltransferase” has been published in an online version of European journal of histochemistry.

Oct. 6-7, 2012    Graduate students Yang Hongkuan and Yang Mingchun gave an oral presentation at the 39th Annual Meeting of the Japan Society of Brain Science at Kitakyushu.

Oct. 6, 2012     Graduate student Yang Hongkuan got a yang investigator award at the 39th Annual Meeting of the Japan Society of Brain Science at Kitakyushu.

Sep. 19, 2012     Graduate student Yang Hongkuan gave an oral presentation at the 35th Annual Meeting of the Japan Neuroscience Society held at Nagoya.

Sep 17, 2012     A paper concerning “Familiar Adult Myoclonic Epilepsy” has been published in an online version of ISRN Neurology.

Sep. 7, 2012     The research findings in collaborative work of Shiga University of Medical Science, Fukushimura hospital and Panasonic Healthcare Co. Ltd. were presented and received Uragami award at the 2nd Annual Meeting of Japan Society for Dementia Prevention.

Aug. 26-29, 2012     MNRC members attended 14th International Congress of Histochemistry and Cytochemistry held at Kyoto.

Jul. 21, 2012　　 A paper concerning gamma-secretase has been published in an online version of Journal of Neurochemistry.

Jul. 19, 2012　　 A paper entitled "In Vivo Detection of Copper Ions by Magnetic Resonance Imaging Using a Prion-Based Contrast Agent" has been published in an online version of Applied Biochemistry and Biotechnology.

Jul. 14-19, 2012     MNRC members attended AAIC 2012.held at Vancouver, Canada.

Jul. 13-14, 2012     Professor Tooyama was invited to the 5th Harbin International Neurosurgical Conference..

Apr. 2, 2012     Four researchers have been employed as new staffs at MNRC.

Mar. 27, 2012　　 A paper concerning ES cell research has been published in an online version of Biochem Biophys Res Commun.

Mar. 7, 2012　　 A paper concerning deposition of beta-amyloid peptides in the nasal cavity of transgenic mouse model of Alzheimer's disease has been published in an online version of Neuroscience Letters.

Feb. 24, 2012 　Dr. Yang Hongkuan, Graduate student, received the judges’ special award for his presentation at the 28th SMUS symposium held on Feb.16, 2012.

Feb. 14, 2012 Seminar by Dr. Joseph S. Tauskela and lunch meeting on cooperative research between MNRC and Nagahama Institute of Bio-Science and Technology were held at Nagahama Institute of Bio-Science and Technology.

Feb. 13, 2012 The 14th MNRC International Symposium entitled “New insights into the treatment of neurological diseases”was held at Shiga University of Medical Science, Otsu.

Jan. 18, 2012 　The 14th MNRC international symposium will be held on Feb. 13, 2012.

Jan. 11, 2012 　MNRC members attended “The Evening for International Exchange”, a social party, held at SMUS.

Dec. 26, 2011 　MNRC members party was held in Boston Pulaza Hotel as the year-end party of 2011.

Nov. 12, 2011　　A paper concerning metals in the brain of Alzheimer's disease (supported by the New Energy and Industrial Technology Development Organization (NEDO), Japan) is published in an online version of Biometals.

Nov. 11, 2011 　Prof. Dr. Raymond Azman Ali, Prof. Dr. Musalmah Mazlan, and Associate.Prof. Dr. Norzilawati Mohd Naim from Universiti Kebangsaan Malaysia Medical Centre visited MNRC.

Oct. 6, 2011 　Dr. Songok and Dr. Mpoke from Kenya Medical Research Institute, and Prof. Omwandho from Ms.Bisem’s home University, Nairobi University, visited MNRC.

Oct. 1, 2011 　 Prof. Ikuo Tooyama, Director of MNRC, and Associate Prof. Makoto Urushitani attended Canada-Japan Cooporation in Science and Technology Ceremony.

Sep. 24-25, 2011 　 Graduate students, Ms.Masuda and Ms.Bisem, presented posters at Japan Society of Histochemistry Meeting.

Sep. 23, 2011　　A study entitled by "NPR-C Protects Embryonic Stem Cells from Apoptosis by Regulating p53 Levels." by Essam M Abdelalim and Ikuo Tooyama has been published in an onlline version of Stem Cells Dev.

Sep. 1, 2011 　 MNRC provides Annual Report 2011(Renewaled;Japanese and English edition).

Jul. 27, 2011　　 A farewell party for Dr. Essam Abdelalim.

Jul. 17, 2011　　 Senior Assistant Professor Akinori Matsuo performed a poster presentation at the 8th IBRO World Congress, Florence, Italy.

Jul. 16-21, 2011　　 MNRC members attended ICAD 2011 held at Paris,France.

Jul. 4, 2011 　 MNRC provides Annual Report 2011.

Jul. 3, 2011　　 A collaborative study between Associate Professor Masaki Nishimura and Riken BSI has been published online in Nature Neuroscience.

Jun. 24-26, 2011 　 Professor Ikuo Tooyama gave a presentation as an invited speaker at the International Conference on cGMP.

Jun. 20, 2011　　A collaborative study between Associate Professor Masaki Nishimura and Hokkaido University has been published in Annals of Neurology.

May. 30, 2011 　 Professor Ikuo Tooyama, Director of MNRC, visited the Harbin Medical University, China, to attend the Ph.D candidates' defense of the dissertation as an external reviewer.

May. 1, 2011　　Associate Professor Makoto Urushitani visited Centre for Research in Neurodegenerative Diseases, University of Toronto,and presented his immunization project in the seminar (Invited by Prof. Janice Robertson).

Apr. 30, 2011　　Associate Professor Makoto Urushitani was officially invited as a guest speaker by ALS Society of Canada, an provided a plenary lecture about the protein misfolding of ALS pathogenesis in the 7th Annual Research Forum at Sheraton Gateway Hotel, Toronto, Canada.

Apr. 19, 2011　　Call for Applications for a Professorship in the Molecular Neuroscience Research Center.

Apr. 12, 2011　　We enjoyed viewing Sakura in Ishiyama temple.

Apr. 12, 2011　　 A paper concerning amyloid imaging using fluorinated MR agents was published in an online version of Neuroscience.

Apr. 1, 2011　　 A paper concerning the distribution of NPR-B in the brain was published in an online version of Brain Struc Funct.

Mar. 24, 2011　　 A farewell party was held in MNRC.

Mar. 15, 2011　　 A seminar was held by Dr. Yasuji Matsuoka (Manager, Neural Pathway Discovery, GlaxoSmithKline, Singapore) entitled by "Gamma-secretase, a therapeutic target for Alzheimer's disease and traumatic brain injury".

Mar. 10, 2011　　 A paper concerning role of NPR-A on ES cells has been published in the online version of Cell Death and Disease.

Feb. 19, 2011　　 A news story concerning Dr. Essam Mohamed Abdelalim appeared on the Chunichi Shimbun.

Feb. 18, 2011　　 A paper concerning curcumin and beta amyloid oligomer has been published in the online version of Journal of Alzheimer's disease.

Dec. 21, 2010 　　A paper concerning the inflammation in the  hippocampal sclerosis ｗas published in Acta HIstochemica et  Cytochemica.

Dec. 16, 2010　　A paper entitled “Nuclear Choline Acetyltransferase Activates Transcriptionof a High-affinity Choline Transporter” has been published in the online version of the Journal of Biological Chemistry.

Dec. 16, 2010 　MNRC members party was held in Boston Pulaza Hotel as the year-end party of 2010.

・Dec. 13, 2010　　Dr. ABDEL-HAMID KAMEL OSMAN Department of Cytology and Histology, Suez Canal University, Ismailia, Egypt, gave a lecture entitled by “APOPTOSIS IN THE MYOCARDIUM OF THE ADULT DROMEDARY CAMEL:ULTRASTRUCTURAL CHARACTERIZATION”.

・Nov. 13, 2010　　Our colleagues presented our recent studies at the 4th Japanese Association for Lactoferrin.

・Oct.17-18, 　Our colleagues presented our recent studies at the 37th Japan Brain Science Society meeting in Tianjin, China.

・Oct.6, 2010 　Dr. Essam M Abdelalim has got an Award from Misr El-kheir Foundation in Egypt ( a non profit organization). The Award is given to the top 50 Egyptian researchers or Egyptian research teams published their work in 2009 as judged by the scientific board.

・Sep.29-Oct.1st, 2010　Professor Ikuo Tooyama presented new drugs for the diagnosis of Alzheimer's disease in Bio Japan 2010 held in Yokohama.

・Sep.15-17,2010 Professor Ikuo Tooyama, Director of MNRC and Assistant Professor Satoshi Makino visited CHINA.

・Sep. 04, 2010 　Dr. Wang and Ms. Bisen attended the 51th annual meetinng for the Japan Society of Histochemistry and Cytochemistry held in Tokyo on September 5, 2010.

・Sep. 1st, 2010 The 13th MNRC International Symposium entitled “How to tackle Misfolded Proteins in ALS”was held at Shiga University of Medical Science, Otsu.

・Jul. 26, 2010 A paper concerning morphological study on lactotoferrin in the brain of Alzheimer's disease has been published in online version of Neuroscience Letters.

Jul. 17-18, 2010 Professor Ikuo Tooyama, Director of MNRC, visited Harbin Medical University.

・Jul. 10-15, 2010 Our colleagues presented our recent studies at ICAD2010 at Honolulu.

・June 1-5, 2010 Professor Ikuo Tooyama, Director of MNRC,visited CHINA.

・May 17, 2010. Dr. Michael J. Zigmond at professor Pittsburgh Institute for Neurodegenerative Diseases of the University of Pittsburgh,,gave a lecture entitled by "Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency."

・May 14, 2010. Dr. Baofeng Yang, a president of Harbin Medical University, and his colleagues paid a courtesy visit to Molecular Neuroscience Research Center.

・May 7, 2010. Professor Tooyama presented the study on "Development of diagnostic drugs for Alzheimer's disease" in the 1st joint meeting of Ritumeikan University and SUMS.

・April 20, 2010. Dr. Seung Kim at professor emeritus of the University of British Columbia, Canada,gave a lecture entitled by "Human neural stem cell-based gene therapy in neurological diseases."

・April 6, 2010 Mr.Liu Lei and Miss Naomi Bisen have entered the graduate course at MNRC, SUMS.

・April 1, 2010 Professor Ikuo Tooyama became a director at MNRC.

・Feb. 28, 2010 　A paper concerning "the tautomeric structures of curcumin derivatives and their Ab-binding activities" has been published in the online version of Biomaterials.

・Feb. 16, 2010 　Signing ceremony for the agreement between University of Ottawa and Shiga University of Medical Science was held with great eclat.President Alan Rock and the members at University of Ottawa were accorded a tremendous welcome.

・Feb. 10, 2010 　Dr. Yanagisawa has received a research award from 10th Bio Business Competition Japan. The research title is "Novel diagnostic drugs for Alzheimer's disease using keto-enol tautomerism." (Biomaterials, in press).

・Dec. 22, 2009 　MNRC members party was held in Boston Pulaza Hotel as a year-end party.

・Dec. 10-15, 2009 Professor Tooyama has presented the study entitled “Expression of lactoferrinand its receptor in the brain of patients with Alzheimer’s disease” as a invited speaker in the first international conference of metal chelating in biology andmedicine, held at Bath, England.

・Dec. 10, 2009 An international study concerning molecular genetics on sporadic ALS hasbeen published in online version of Proc. Natl. Acad. Sci.

・Dec. 4-5, 2009 Ms. Masuda, Ms Naomi Bisen and Dr. Wang Liang visited Hiroshima to learn Japanese Culture and History.

・Nov. 11, 2009 Professor Tooyama has been invited to give a lecture concerning new drugsfor the diagnosis of Alzheimer’s disease at Department of Pharmacology, Tohoku University.

・Oct. 7, 2009 Dr.Wang Ligang has joined in our research team as a doctoral fellow from Harbin Medical University.

・Oct. 2, 2009 A paper concerning the clearance of polyubiquitinated TDP-43has been published in Journal of Neuroscience Research.

・Sep. 28, 2009 A paper concerning TDP-43 in motor neuron has been publishedin Neuroscience.

・Sep. 17, 2009 Professor Tooyama presented new drugs for the diagnosis of Alzheimer'sdisease in Innovation JAPAN 2009 held in Tokyo.

・Aug. 17, 2009 A paper concerning C7orf24 has been published in J Histochem and Cytochem as an advance online publication.

・Aug. 11, 2009 A collaborated study between MNRC (Dr. Urushitani) and Canada has been published in Glia as an advance online publication.

・Jul. 13-17, 2009 Our colleagues presented our recent studies at ICAD2009 at Wien.

・June. 24, 2009 The 12th MNRC International Symposium entitled “Functional Analysis of Neural Network; from cell to the brain”washeld at Shiga University of Medical Science, Otsu.

・June. 1, 2009 Dr. Makoto Urushitani has been selected as an associate professor at Unit for Neurobiology and Therapeutics, Molecular Neuroscience Research Center.

・May. 21, 2009 Dr. Urushitani presented "The development of immunotherapy for ALS" at the　symposium of the 50th Annual Meeting of the Japanese Society of Neurology held in Sendai, Japan.

・Apr. 14, 2009 The research paper concerning role of BNP on ES cells has been accepted for publication in PLoS ONE.

・Apr. 7, 2009 Mr Vigers and Ms. Kmeshima have joined us as graduate students (PhD course).

・Apr. 6, 2009 Ms. Naoimi Bisen has joined us as a foreign student from Keniya.

・ Mar. 25, 2009 Dr. Essam M Abdelalim graduated from the PhD course and got the degree of PhD at SUMS.

・Mar. 23, 2009 The co-operative research on DJ-1 molecules with Kyoto Pharmaceutical University and Hokkaido University has been accepted by Oxidative Medicine and Cellular Longevity.

・Feb. 20, 2009 A central the 11th molecular neuroscience research international symposium is held from 1:30PM, to 3:40 in the second floor in basic building schoolpersonnel lobby.

・Jan. 30, 2009 The research paper concerning lactotransferrin in the brain of Alzheimer's disease has been accepted for publication in NeuroscienceLetters.

・ Nov. 20, 2008 The research paper, "Axotomy Alters Alternative Splicing of Choline Acetyltransferase in the Rat Dorsal Motor Nucleus of the Vagus Nerve", has been accepted for publication in The Journal of Comparative Neurology.

・ Nov. 4-7, 2008 Professor Tooyama visited North East University and China Medical University as a official member of Shiga University of MedicalScience (Leader; Hattori Vice-President).

・ Oct. 3, 2008 The research paper concerning fluorinated MR contrast agents for amyloid imaging has been accepted by Neuroscience Research.

・ Jun. 19, 2008 The research paper concerning Natriuretic Peptide ReceptorC has been accepted for Neuroscience.

・ Jun. 16, 2008 The research paper concerning pChAT has been accepted for Journal Comp Neurol.

・ Jun. 13, 2008 Dr. Saito, a postgraduate student, has got an award for the young scientist from the Japan Society of Brain Science.

・ Jun. 10, 2008 Mr.EssamAbdelalim, a postgraduate student, presented his work on Embryonic Stem Cells in The First Japan-Egypt International Symposium on Science and Technology in Tokyo.

・ May. 2, 2008 The research paper , collaborating between Rome University and Shiga University of Medical Sicence, concerning cholinergic c system in Octopus vulgaris has been accepted for Journal Comp Neurol.

・ May. 1, 2008 The Japan Society of Science Promotion has announced grants from The Ministry of Education, Science, Sport, Culture and Technology at 2008. Four researches in MNRC have got the grants.
　　1) Grant-in Aid for Scientific Research (B): 2008-2010 (Prof. Kimura)
　　2) Grant-in Aid for Young Scientist (B): 2008-2010 (Assistant Prof. Bellier)
　　3) Grant-in Aid for Scientific Research (B): 2007-2009 (Prof. Tooyama)
　　4) Grant-in Aid for Scientific Research (B): 2007-2009 (Assistant Prof.Urushitani)

・ Apr. 29, 2008 The research concerning Natriuretic Peptide Receptors in the retna has been published in Peptides.

・ Mar. 28, 2008 The collaborating research for DJ-1, a Parkinson disease-related protein, has been published in J Cereb Blood Flow Metab.

・ Mar. 12, 2008 The research concerning a pathogenesis of ALS has been published in FASEB Journal.