Prof. Seiji Hitoshi, M.D., Ph.D.
Education
1988 : M. D., Fuculty of Medicine, University of Tokyo
1997 : Ph. D., Graduate School of Medicine, University of Tokyo
Professional Appointments
2011- : Professor, Department of Integrative Physiology, Shiga University of
Medical Science
2003-2011 : Associate Professor, National Institute for Physiological Sciences
2001-2003 : Assistant Professor, Department of Neurology, University of Tokyo
1999-2001 : Postdoctoral Fellow, Department of Anatomy and Cell Biology
University of Toronto
1997-1999 : Special Postdoctoral Researcher, the Institute of Physical and Chemical
Research (RIKEN)
1992-1993 : Neurologist, Tokyo University Hospitals
1991-1992 : Neurologist, Tokyo Metropolitan Geriatric Medical Center
1990-1991 : Neurologist, Japan Red Cross Medical Center
1988-1990 : Resident physician, Tokyo University Affiliated Hospitals
Research Interest
Developmantal Neurobiology; Adult Neurogenesis and Neurological and Psychiatric Diseasses, Autoimmune Neurological Diseases
Selected publications
- Hitoshi S, Ishino Y, Kumar A, Jasmine S, Tanaka KF, Kondo T, Kato S, Hosoya T, Hotta Y, Ikenaka K. (2011) Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells. Nat Neurosci 14, 957-964
- Hitoshi S, Alexon T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D. (2002) Notch pathway molecules are essential for the maintenance, but not for the generation, of mammalian neural stem cells. Genes & Dev. 16, 846-858
- Hitoshi S, Kusunoki S, Kanazawa I, Tsuji S. (1995) Molecular cloning and expression of two types of rabbit β-galactoside α1,2-fucosyltransferase. J Biol Chem 270, 8844-8850
- Hitoshi S, Iwata M, Yoshikawa K. (1991) Midbrain pathology of Wilson's disease: MRI analysis of three cases. J Neurol Neurosurg Psychiat 54, 624-626
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